Concerning pathological stage, CAMK2N1 (p<0.001), CD44 (p=0.020) and WNT5A (p<0.001) expression levels were significantly higher in locally advanced (pT3b-PCa) compared to organ-confined (pT2a+b-PCa) disease (Figure 1A, C and E), but no significant differences for KRT14 and TGFB3 were depicted. This evidence concerns the gene CD44 and posterior cortical atrophy.