Among gene deregulations associated with type 2 diabetes are SIRT1, transcription factor 7-like2 (TCF7L2), Potassium channel gene (KCNJ11), Glucocorticoid receptor (GRL), and Norepinephrine transporter (NET) (Karbasforooshan and Karimi, 2017[91]). This evidence concerns the gene SLC6A2 and type 2 diabetes mellitus.