Among them, BAX, BIRC5, ITGA2, and MYB were identified as significantly correlated with the survival of patients with HCC, which was in line with the results of previous studies [28, 44–46], while PRKAA2, PTGIS, PDE7B, CYP8B1, CHEK1, CAMK4, ASPA, and ACSM2A were identified to predict the prognosis of patients with HCC for the first time. The gene discussed is PTGIS; the disease is hepatocellular carcinoma.