However, stromal CD34‐positivity was preferably found in pulmonary adenocarcinoma (ADC 51.8% positivity vs. SCC 34.2% positivity vs. LCC 30.4% positivity; P = 0.006) and was more common in differentiated tumors than in undifferentiated ones (G1 100% positivity, G2 45.7% positivity, G3 40.4% positivity, G4 15.8% positivity; P = 0.002). This evidence concerns the gene CD34 and leukoencephalopathy with calcifications and cysts.