NFKB1 and cancer: It has been well established that NF-κB plays a pivotal role in inflammatory and immune responses and regulates the expression of a variety of important genes associated with different hallmarks of cancer (Manu et al., 2011; Shanmugam et al., 2011b; Manu et al., 2012; Li et al., 2013; Li et al., 2015a; Li et al., 2015b; Monisha et al., 2017; Ningegowda et al., 2017) .