NFKB1 and cancer: It was found to exhibit the effect by suppressing NF-κB in different cancer cell lines such as breast, bladder, hepatoma, lung, leukemia, pancreatic, and prostate (Pandey et al., 2007; Zhang et al., 2008; Chua et al., 2010; Moon et al., 2010a, Moon et al., 2010b; Ishikawa et al., 2017).