FGFR2 and breast cancer: There is no similar study that discusses the relationship of early onset of breast cancer and FGFR2 polymorphism in other populations, but a study by Liang (Liang et al., 2008) found that there is a strong association of TT mutant genotypes and T alleles in FGFR2 polymorphism rs2981582 as risk factors of occurrence of BC in premenopausal women.