One of the major risk factors for early onset BC is a history of BC in the family, which involves inherited genetic mutations, in particular the major susceptibility genes BRCA1 and BRCA2. However, BRCA1 and BRCA2 have been shown to account for up to only 15% of familial early onset BC cases (Stratton and Rahman, 2008). This evidence concerns the gene BRCA2 and breast cancer.