PTEN and breast cancer: In one study, the aberrant expression of circRNA MYLK promoted BC progression by modulating the VEGFR2/VEGFA signaling pathway.12 Furthermore, the circRNA ITCH inhibited BC progression by sponging miR‐224/miR‐17 and regulating PTEN and p21 expressions.13 Previous studies found a series of differences and characterizations in circRNA expression profiles between bladder carcinoma tissues and adjacent noncarcinoma tissues using high‐throughput microarray assay.