Other variables with a p < 0.2 in the univariate analysis were age >75, ASA class III/IV, diabetes, arrhythmia, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, use of diuretics, use of statin, use of insulin, use of antiplatelet agents, duration of surgery, intraoperative nitroglycerin infusion, last measured intraoperative mean arterial pressure, last measured intraoperative central venous pressure and application of mechanical assist device. Here, INS is linked to chronic obstructive pulmonary disease.