PDLIM2 and lung carcinoma: To this end, our analysis of the TCGA data indicated that expression of major histocompatibility complex class I (MHC-I) genes was decreased in human lung cancers, and that PDLIM2 expression was associated positively with T-cell activation and expression of MHC-I genes in human lung cancers but not in normal lung tissues (Fig. 5a, Supplementary Fig. 6a–c, Supplementary Tables 4, 5).