Higher-level expression of miR-378 in ovarian cancer cells than in normal ovarian surface epithelial cells has been described, together with an associated dysregulation of several angiogenesis genes, such as activated leukocyte cell adhesion molecule (ALCAM), EH-domain containing 1 (EHD1), serine/threonine-protein kinase tousled-like 1 (TLK1), and the transcriptional repressor ELK3 (ETS Transcription Factor ELK3) [69]. The gene discussed is TLK1; the disease is ovarian cancer.