Finally, another report in acute erythroid and acute megakaryoblastic leukemia pointed towards this direction, which showed that the LSD1 inhibitor T-3775440 acted by disrupting the LSD1-Gfi1b interaction in vitro, leading to growth inhibition and differentiation; however, the authors did not address the role of LSD1’s demethylase activity in the process [90]. The gene discussed is KDM1A; the disease is acute megakaryoblastic leukemia.