In the subgroup analysis, expression levels of eIF4E, p-PI3K, p-AKT, p-mTOR, p-4EBP1, p-eIF4E, p-S6K1, and p-S6R in the tumor specimens of patients with or without recurrence were analyzed using IHC staining and quantified by semi-quantified scoring systems. This evidence concerns the gene EIF4E and neoplasm.