Both the in vivo and the in vitro data suggest that the GSS has anti‐apoptotic effects on LPS‐induced lung vascular EC injury via TLR4/ Myd88/NF‐κB/BCL‐2 signalling, which may be the main reason why GSS effectively alleviates sepsis‐induced ALI. The gene discussed is MYD88; the disease is Sepsis.