GO analysis demonstrated that genes (WNT9A, NOTCH3, SOCS1, MCL1, HIF1A, ALOX5, CD47, CXCR4, CDK9, HRAS, PLK3, ETS2 and RPL5) involved in “acute and chronic myeloid leukaemia,” “bladder cancer,” “hedgehog signalling pathway,” “endometrial cancer” and “basal cell carcinoma” signalling pathways were significantly correlated with the DDIT4 expression. This evidence concerns the gene PLK3 and chronic myelogenous leukemia, BCR-ABL1 positive.