To examine whether the impact of DDIT4 expression on AML survival was independent, we constructed multivariate Cox proportional hazard models using multiple variables, including DDIT4 expression (high vs low), WBC count (≥15 vs <15 × 109/L), age (≥60 vs <60 years), BM blasts (≥70 vs <70%), PB blasts (≥20 vs <20%), NPM1 (mutated vs wild), DNMT3A (mutated vs wild), TET2 (mutated vs wild), TP53 (mutated vs wild) and FLT3‐ITD (positive vs negative) (Table 2). The gene discussed is FLT3; the disease is acute myeloid leukemia.