LARS1 and obesity due to melanocortin 4 receptor deficiency: Particularly, recent studies have also been shown the aminoacyl‐tRNA synthetases to be promising targets in the development of antimicrobial agents37 as well as in therapeutics against cancers and other diseases.32 Then, LARS might serve as a potential anti‐obesity target and that the nutritional signalling pathway may provide a valuable anti‐obesity strategy for further investigation.