MicroRNAs were found to be key middle-regulators participating in the modulatory network of some tumor-related genes.27–29 To investigate the effect of FOXO1 on miRNAs in NPC, we used miRNA chip data and qPCR to screen differential miRNAs and found that miR-200b was significantly upregulated in FOXO1-overexpressing NPC cells. Here, FOXO1 is linked to nasopharyngeal carcinoma.