Further, western blotting assays showed that the expression levels of p-PI3K, p-AKT, c-Myc, and MYH9 were upregulated, while the expression level of P53 was suppressed after knocking down FOXO1 in FOXO1-overexpressing NPC cells (Supplementary Fig. S3M). Here, MYC is linked to nasopharyngeal carcinoma.