In previous studies, miR-200b had been reported to target BMI-1 and ZEB1 (and others) and suppress tumor stemness and EMT.30,31 In this study, we observed that suppressing miR-200b in FOXO1-overexpressing NPC cells restored tumor stemness, migration, and invasion through downregulation of ZEB1. This evidence concerns the gene BMI1 and nasopharyngeal carcinoma.