APBB1 and neoplasm: Hsa-mir-34a was reported as a tumor suppressor gene by inhibiting non-small cell lung cancer (NSCLC) growth and suppressing the CD44hi stem-like NSCLC cells.31,32 We found that a meta-path of hsa-mir-34a-SAA1-APBB1 may involve in the lung cancer-associated asthma by meta-path-based network analysis within the human protein–protein interactome (Fig. 6).