When comparing the mean and maximum 89Zr-DFO-CD4 tumor-to-heart ratios of responders (N=5) and non-responders among all mice (N=30), irrespective of tumor model, a significantly increased maximum 89Zr-DFO-CD4 tumor-to-heart ratio was found in the responders (p=0.0306) (Figure 6C, top panel). This evidence concerns the gene CD4 and neoplasm.