We have confirmed our previous findings that the third generation TKI osimertinib instead of inhibiting, induces STAT3 and YAP1 (PC9 and H1975) in addition to Src and CDCP1 phosphorylation (only PC9) in the PC9 and H1975 EGFR-mutation positive NSCLC cell lines 8-10. This evidence concerns the gene STAT3 and non-small cell lung carcinoma.