PHKB and hepatocellular carcinoma: Univariate analysis showed that macrovascular invasion (RR=2.19, 95%CI=1.13-4.28, P=0.021), microvascular invasion (RR=1.91, 95%CI=1.21-3.04, P=0.006), BCLC stage (RR=1.72, 95%CI=1.01-2.94, P=0.045) and PHKB (RR=2.212, 95%CI=1.269-3.846, P=0.005) were associated with recurrence and overall survival of HCC patients (Table 2).