L1CAM and metastatic malignant neoplasm in the lymph nodes: Interestingly, elevated L1CAM expression in GC tissues was an independent risk factor for both lymph node metastasis (odds ratio (OR), 2.18; 95% CI, 1.03–4.63; p = 0.0042, Table 2c) and distant metastasis (OR, 3.88; 95% CI, 1.74–8.65; p = 0.0009, Table 2d).