Compared with healthy volunteers, the extremely high serum levels of MMP-9 and CCL21 in patients with colon cancer [50], of CCL11 in patients with gastric cancer [31], of CCL2/MCP-1 in patients with breast cancer [51] and of CXCL13 in patients with liver cancer [34] have been reported. Here, CCL2 is linked to colonic neoplasm.