Of note, we did not detect a significant difference in the response to steroids between patients with anti-paranodal IgG4 antibodies and seronegative patients, confirming steroids as an effective therapeutic option in CIDP cases, independent from their serologic status for anti-Nfasc155, CNTN1, or Caspr1 antibodies. This evidence concerns the gene CNTN1 and chronic inflammatory demyelinating polyradiculoneuropathy.