The most common grade 3/4 treatment-related AEs were fatigue/asthenia (2%), anemia (1%), increased transaminases (2%), increased lipase/amylase (1%), dyspnea (1%), and pneumonitis (1%) in BoM+ patients, and fatigue/asthenia (2%), pain (1%), and dyspnea (1%) in BoM- patients. Here, GRHL2 is linked to anemia.