WDR5 and breast carcinoma: WDR5 silencing induced a significant reduction of cell motility with respect to the control (shLuc) (Fig. 3c), quantified as displacement (μm) in the box plots (about 40%) (***: p value < 0.001) (Fig. 3d), suggesting that WDR5 regulates breast cancer cell motility, as previously observed in other systems [42].