While the impact of genetic ablation or inactivation of PI3K-C2β on transgenic cancer models has not been assessed yet, evidence now supports the conclusion that PI3K-C2β might play a role in several cancer types [46–55], mainly through regulation of cancer cell migration [46, 50–53], invasion [50, 52] and metastasis formation [50, 54]. Here, SCGB2B3P is linked to cancer.