The HER2 status is involved in the subtyping of breast cancer, in detail composed of luminal A (HER-, ER+, low proliferation), luminal B (HER+ or -, ER+, high proliferation), HER2-type (HER2+, ER+ or -) and basal like (triple negative breast cancer) [76]. This evidence concerns the gene ERBB2 and breast carcinoma.