TNFSF13B and systemic lupus erythematosus: Taking into account disease activity of SLE at the time of inclusion, patients with the BAFF-var allele exhibited severe disease as assessed by the attending physician (and subsequently defined as PGA ≥ 2) more frequently (7 of 14, 50%) than did those without this allele (24 of 139, 17%) (p = 0.002; OR, 4.8; 95% CI, 1.54–14.93) (Table 3).