Heavy pill burden, fear of stigma and discrimination, cost and access to transportation, medication side effects, economic problems in the household, long travel due to distance from ART clinics, long waiting times, alcohol drinking, smoking, being with baseline CD4 < 200 cells/mm3, having mental illness, being bed ridden functional status, and dissatisfaction with healthcare services were risk factors for ART discontinuation. Here, CD4 is linked to psychiatric disorder.