In the GSE94601 dataset, the 19 and 4 poorly differentially samples initially assigned to the LCC subtype were reclassified to pADC and pSCC with the positive expressions of ADC markers (NAPSA/TTF1) and SCC markers (Krt5/P40), respectively. Here, SERPINB3 is linked to leukoencephalopathy with calcifications and cysts.