The protective effects have multiple mechanisms including reducing hepatic lipid deposition, decreasing endotoxemia, reducing oxidative stress, anti-inflammatory effects through the modulation of nuclear factor kappa B (NF-κB) and tumor necrosis factor (TNF), and antifibrotic effects through the modification of transforming growth factor-beta (TGF-β) and collagen expression [84,85,86,87,88]. The gene discussed is TNF; the disease is serum lipopolysaccharide activity.