ING4 and metastatic malignant neoplasm in the lymph nodes: ING4 expression also correlated with lymph node metastasis in lung [73], colorectal [74], ovarian [75], and clear-cell renal carcinomas [76] and was implicated in prostate epithelial cell differentiation, where loss of ING4 increased the levels of myc-induced prostate oncogenesis [77].