All the variants described (Figure 5A–C) in NMOsd patients were also observed in the small population of MS patients we analyzed here, except for one variant in the 5′UTR of the AQP1 gene observed in one patient with NMOsd(–), and in three of the four variants found in the coding region of the AQP4 gene (rs72557968, rs1839318 and rs72557975), that we observed only in NMOsd(+) patients (Table 2). The gene discussed is AQP1; the disease is myeloid sarcoma.