Similarly, the Randomized Evaluation of Dual Antithrombotic Therapy with Dabigatran versus Triple Therapy with Warfarin in Patients with Nonvalvular Atrial Fibrillation Undergoing Percutaneous Coronary Interventio trial [79], randomized 2725 patients with AF who had undergone PCI to triple therapy with warfarin plus a P2Y12 inhibitor (clopidogrel or ticagrelor) and aspirin, or to dual therapy with dabigatran (110 mg or 150 mg twice daily) plus a P2Y12 inhibitor (clopidogrel or ticagrelor, at the discretion of the treating physician) and no aspirin (110-mg and 150-mg dual-therapy groups). This evidence concerns the gene P2RY12 and atrial fibrillation.