Following studies in Canada [17], the United States [18,19], Israel [20] and Germany [21] all of which showed GDM becoming more prevalent in the first decade of this century, our recent analysis of women recruited to the Cambridge Baby Growth Study (CBGS) in this same decade showed a significant increase in the incidence of GDM that was associated more with a temporal reduction in indices of insulin secretion than insulin sensitivity [22]. Here, INS is linked to gestational diabetes.