APOB and chronic kidney disease: In the course of chronic kidney disease the following disturbances are frequently observed: elevated levels of VLDL, IDL, triglycerides, normal to increased levels of LDL, but at the same time elevated concentrations of oxidized LDL, HDL deficiency and dysfunction, diminished levels of apolipoprotein A-1, the accumulation of apolipoprotein B (Apo B)-containing lipoproteins, as well as higher apolipoprotein C-III/C-II ratio [7].