The correlation between VEGF-A SNPs and treatment efficacy was also examined in patients receiving bevacizumab and sorafenib for recurrent glioblastoma; mutant VEGF-A allele rs699947 was associated with a 6 month increase in PFS whilst mutant VEGF-A rs1570360 was associated with a 6 month decrease in PFS [30]. Here, VEGFA is linked to glioblastoma.