Similar to dystrophin, other molecules have been identified to be involved in the maintenance of membrane stability, such as dysferlin, a protein involved in membrane repair processes that, when altered, determines the limb-girdle muscular dystrophy type 2B (LGMD2B), characterized by chronic muscle inflammation and damage [6]. The gene discussed is DYSF; the disease is autosomal recessive limb-girdle muscular dystrophy type 2B.