LYZ and amyotrophic lateral sclerosis: Regarding the relationship between Paneth cells and butyric acid, it was reported that the Paneth cell number, HD5 mRNA and lysozyme mRNA expression, were decreased in an amyotrophic lateral sclerosis mouse model, and were recovered by administration of 2% butyric acid in the drinking water to the same levels as those in wild-type mice following [31].