In this respect, overexpression of TLR4 after LPS challenge in mice or mouse lung fibroblasts was shown to significantly contribute to the induction of pulmonary fibrosis.68, 69 Taken together, we speculate that the ability to inhibit crucial players (IFN‐γ, IL‐4, and IL‐13 cytokines; TLR4 expression) involved in the induction of fibrosis rather supports the idea of a beneficial regulatory property for the mimetic peptide. Here, IL4 is linked to pulmonary fibrosis.