INS and Glucose intolerance: Therefore, we used bulk mRNA from pancreatic islets of humans stratified for glucose intolerance (Uhlen et al, 2005; Fadista et al, 2014), which shows that PET1/FEV expression indeed correlated with that of INS (R = 0.41, P = 4.7e−9; Fig EV5E) and was differentially expressed between non‐diabetic and type 2 diabetic donor islets (Appendix Fig S5A and A1).