Besides heat stress (Baena et al., 2018; Sales et al., 2018), heat shock proteins (HSP) are being evaluated in apoptosis, oxidative stress, inflammatory diseases, cancer (Ikwegbue et al., 2017), virus infection (Shan et al., 2018), bacterial infection (Kim et al., 2018), as immunomodulators (Edkins et al., 2017; Zininga et al., 2018), therapeutics (Skórzynska-Dziduszko et al., 2018), and diagnostics (Lechner et al., 2018; Tang T. et al., 2018). This evidence concerns the gene HSP90B2P and cancer.