Analyzing the data of lung adenocarcinoma samples and matched normal control tissues obtained from The Cancer Genome Atlas (TCGA) online resource, we found that the mRNA expression of ARL14 in lung adenocarcinoma samples was significantly higher than that in the matched normal tissues (Figure 1A, N = 57, fold change = 2.3, P = 1.23E-06), and the expression of ARL14 in adenocarcinoma had a very strong negative correlation with the overall survival of those lung cancer patients (Figure 1B, N = 482, P = 4.12E-04). This evidence concerns the gene ARL14 and adenocarcinoma.