Compared to those in the healthy controls, the leptin levels were significantly higher in the low-grade liver steatosis group (median [IQR], 20.06 [10.26–22.61] ng/mL vs. 6.84 [1.48–10.26] ng/mL, P < 0.001) but not in the high-grade liver steatosis group (median [IQR], 10.97 [5.13–20.51] ng/mL vs. 6.84 [1.48–10.26] ng/mL, P = 0.435) (Figure 1C). Here, LEP is linked to fatty liver disease.