The overexpression of DKC1 and RUVBL1 in s-CRC is more prominent in MSS, than in MSI (adjusted p < 0.05, Figure 6B), which explains the less pronounced activation of the DKC1 branch in MSI s-CRC (Figure 3H) and presumably also the lower variability of TEL activity in MSI compared to MSS (Figure 4). Here, ETV6 is linked to colorectal carcinoma.