KEGG analysis demonstrated that the target genes of differently expressed miRNAs were primarily assigned to 20 pathways, among which, mitogen-activated protein kinase (MAPK) and cyclic guanosine monophosphate-protein kinase G (cGMP-PKG) signaling pathways were mainly involved in exosomal miRNA functions in CRC (Figure 2C). Here, WNK2 is linked to colorectal carcinoma.