Results revealed that DMF might suppress tumor proliferation by diminishing these CD133-marked glioblastoma stem cells (GSCs) in the tumor.   42  These findings warrant further studies on the DMF effects on several hallmarks of GSCs in more detail as new approaches to isolate and characterize tumoral cells that satisfy the functional characteristics of GSCs continue to be explored.43,44. The gene discussed is PROM1; the disease is glioblastoma.