ADIPOQ and obesity due to melanocortin 4 receptor deficiency: Thus, based on our data about hypertrophy and hyperplasia of the fat cells, we can infer that melatonin may act as a blocker agent in the development of pathological obesity, since the formation, and presence of smaller and more numerous adipocytes brings benefits to the individual, for example, expressing more adiponectin, as we observed in this study (Figure 4C).