TGFB1 and diabetic cardiomyopathy: Diabetic cardiomyopathy could be used as a paradigm to outline this complex picture in which microvascular driven-diastolic dysfunction results from the conjunction of the production of advanced glycation end-products (AGEs) that modify the composition of extracellular matrix (ECM) by activating profibrotic transforming growth factor beta (TGF-β) pathway.