A clinical study found ATG7 variants in neurological diseases (Chen et al., 2013), and it has been suggested that changes in ATG7 protein expression and polymorphisms in ATG genes are associated with aberrant autophagy activity and contribute to the pathological processes of these diseases (Pang et al., 2012; Chen et al., 2013; Agler et al., 2014; Xie et al., 2016; Wang et al., 2017; Xu et al., 2017). Here, ATG7 is linked to nervous system disorder.